Phase 1 / benchmark slices

SimpleFold-3B provisional benchmark slices

First target-level SimpleFold-3B benchmark evidence. These rows are now pre-freeze evidence inside the Phase 1A frozen set.

Targets scored

3 / 3
All current provisional slice targets produced predictions and scores.

Median runtime

390 s
Cached SimpleFold-3B CLI runs on M3 Max.

Median peak RSS

38.5 GB
Observed target-level memory is not constant.

Results

TargetBinLengthpLDDTWall clockPeak RSSsequence-aligned lDDTTM-scoreRMSDAligned residues
11BC:Chard11681.2384337.455 s41.4060 GB0.74920.65691.9763
13EE:Amid16181.6716401.635 s38.5429 GB0.85820.92121.68148
13FT:Amid22892.9916390.276 s31.2522 GB0.89150.95881.23212

Interpretation

The first cards exposed a residue-numbering scoring artifact: model predictions were numbered from residue 1 while reference PDB chains retained source numbering. The public cards now use single-chain sequence-aligned lDDT. The hard-bin 11BC:C slice adds an alignment-coverage caveat: only 63 reference residues aligned, so lDDT must be interpreted with coverage visible. These corrections are methodological findings, not final cross-model biological conclusions.

Artifacts

Boundary

These runs are scientific benchmark evidence, but they are not the full Phase 1A result by themselves. They are marked as pre-freeze evidence; the full Phase 1A run is now complete, external biological review is still pending, and cross-model claims are out of scope.